Dr. David Karow and Anders Dale, PhD revolutionize prostate cancer diagnosis with MR Technology
August 12, 2014
MRI technology was used to identify and locate a probably tumor (outlined in yellow) during a targeted prostate biopsy for a patient who had previously had multiple negative biopsies but had persistently high PSA levels. Resulting biospy confirmed presence of high-grade cancer. [read more]
UCSD Radiology Masters PROMO Imaging
August 19, 2014
PROMO is a revolutionary prospective motion-artifact reducing MRI technique developed by Anders Dale and his team. It works by monitoring head position every second or so and adjusting the gradients so the head is always centered relative to the gradients.
UCSD Radiology uses RSI Imaging to Hunt Down the Extent of Tumors
August 20, 2014
Restriction Spectrum Imaging (RSI), an advanced diffusion-weighted imaging technique developed at the Multimodal Imaging Laboratory by Dr. Anders Dale and Dr. Nathan White, overcomes many of the known limitations of standard DWI by separating different components of the diffusion signal, allowing one to disambiguate the slow (restricted) diffusion associated with tumor cellularity and axons from the fast (hindered) diffusion that is often influenced by edema and other non-tumor tissue in the extracellular matrix.
Isolating this slow, restricted diffusion component with RSI can significantly 1) improve tumor conspicuity in patients with high-grade primary and metastatic brain tumors, 2) improve fiber tracking through regions of peritumoral edema and 3) facilitate the interpretation of tumor response on imaging following treatment with antiangiogenic agents, compared to standard DWI and DTI.
Dr. David Karow, working with Dr. Dale, has developed RSI techniques for the evaluation of prostate cancer, providing the urologists with the first-ever ability to perform image-guided MR biopsies of the prostate, directly targeting the areas worrisome for prostate cancer.